The AMPK activator R419 improves exercise capacity and skeletal muscle insulin sensitivity in obese mice

OBJECTIVE: Skeletal muscle AMP-activated protein kinase (AMPK) is important for regulating glucose homeostasis, mitochondrial content and exercise capacity. R419 is a mitochondrial complex-I inhibitor that has recently been shown to acutely activate AMPK in myotubes. Our main objective was to examin...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Mol Metab
Main Authors: Marcinko, Katarina, Bujak, Adam L., Lally, James S.V., Ford, Rebecca J., Wong, Tammy H., Smith, Brennan K., Kemp, Bruce E., Jenkins, Yonchu, Li, Wei, Kinsella, Todd M., Hitoshi, Yasumichi, Steinberg, Gregory R.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
Assuntos:
Brief Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4563030/
https://ncbi.nlm.nih.gov/pubmed/26413470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2015.06.002
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados