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Transfer of chloramphenicol-resistant mitochondrial DNA into the chimeric mouse

The mitochondrial DNA (mtDNA) chloramphenicol (CAP)-resistance (CAP(R)) mutation has been introduced into the tissues of adult mice via female embryonic stem (ES) cells. The endogenous CAP-sensitive (CAP(S)) mtDNAs were eliminated by treatment of the ES cells with the lipophilic dye Rhodamine-6-G (R...

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Bibliografiske detaljer
Main Authors: Levy, Shawn E., Waymire, Katrina G., Kim, Yoon L., MacGregor, Grant R., Wallace, Douglas C.
Format: Artigo
Sprog:Inglês
Udgivet: 1999
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3049807/
https://ncbi.nlm.nih.gov/pubmed/10481313
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