Spectrum of cisplatin-induced mutations in Escherichia coli.
Using a forward-mutation assay based on the inactivation of the tetracycline-resistance gene located on plasmid pBR322, we have determined the mutation spectrum induced in Escherichia coli by cisplatin [cis-diamminedichloroplatinum(II)], a widely used antitumor drug. Cisplatin is known to form mainl...
Shranjeno v:
| izdano v: | Proc Natl Acad Sci U S A |
|---|---|
| Principais autores: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
1987
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304955/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3295870/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.11.3758 |
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