Spectrum of cisplatin-induced mutations in Escherichia coli.

Using a forward-mutation assay based on the inactivation of the tetracycline-resistance gene located on plasmid pBR322, we have determined the mutation spectrum induced in Escherichia coli by cisplatin [cis-diamminedichloroplatinum(II)], a widely used antitumor drug. Cisplatin is known to form mainl...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Burnouf, D, Duane, M, Fuchs, R P
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1987
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304955/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3295870/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.11.3758
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