An unrestrained proinflammatory M1 macrophage population induced by iron impairs wound healing in humans and mice

Uncontrolled macrophage activation is now considered to be a critical event in the pathogenesis of chronic inflammatory diseases such as atherosclerosis, multiple sclerosis, and chronic venous leg ulcers. However, it is still unclear which environmental cues induce persistent activation of macrophag...

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Main Authors: Sindrilaru, Anca, Peters, Thorsten, Wieschalka, Stefan, Baican, Corina, Baican, Adrian, Peter, Henriette, Hainzl, Adelheid, Schatz, Susanne, Qi, Yu, Schlecht, Andrea, Weiss, Johannes M., Wlaschek, Meinhard, Sunderkötter, Cord, Scharffetter-Kochanek, Karin
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3049372/
https://ncbi.nlm.nih.gov/pubmed/21317534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI44490
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