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MSCs rescue impaired wound healing in a murine LAD1 model by adaptive responses to low TGF‐β1 levels

Mutations in the CD18 gene encoding the common β‐chain of β2 integrins result in impaired wound healing in humans and mice suffering from leukocyte adhesion deficiency syndrome type 1 (LAD1). Transplantation of adipose tissue‐derived mesenchymal stem cells (MSCs) restores normal healing of CD18(−/−)...

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Detalhes bibliográficos
Publicado no:EMBO Rep
Principais autores: Jiang, Dongsheng, Singh, Karmveer, Muschhammer, Jana, Schatz, Susanne, Sindrilaru, Anca, Makrantonaki, Evgenia, Qi, Yu, Wlaschek, Meinhard, Scharffetter‐Kochanek, Karin
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7132342/
https://ncbi.nlm.nih.gov/pubmed/32080965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201949115
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