Activated macrophages are essential in a murine model for T cell–mediated chronic psoriasiform skin inflammation

The CD18 hypomorphic (CD18(hypo)) PL/J mouse model clinically resembling human psoriasis is characterized by reduced expression of the common chain of β(2) integrins (CD11/CD18) to only 2–16% of WT levels. Previously we found that this chronic psoriasiform skin inflammation also depends on the prese...

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Autori principali: Wang, Honglin, Peters, Thorsten, Kess, Daniel, Sindrilaru, Anca, Oreshkova, Tsvetelina, Van Rooijen, Nico, Stratis, Athanasios, Renkl, Andreas C., Sunderkötter, Cord, Wlaschek, Meinhard, Haase, Ingo, Scharffetter-Kochanek, Karin
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2006
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1523400/
https://ncbi.nlm.nih.gov/pubmed/16886059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI27180
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