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A Non-Motor Microtubule Binding Site In Kinesin-5 Is Required For Filament Crosslinking And Sliding
Kinesin-5, a widely conserved motor protein required for assembly of the bipolar spindle in vertebrates, forms homotetramers with two pairs of motor domains positioned at opposite ends of a dumbbell shaped molecule [1–3]. It has long been assumed that this configuration of motor domains is the basis...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3049310/ https://ncbi.nlm.nih.gov/pubmed/21236672 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2010.12.038 |
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