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Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications

Genome integrity is constantly monitored by sophisticated cellular networks, collectively termed the DNA damage response (DDR). A common feature of DDR proteins is their mobilization in response to genotoxic stress. Here, we outline how the development of various complementary methodologies has prov...

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Detalhes bibliográficos
Main Authors: Polo, Sophie E., Jackson, Stephen P.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3049283/
https://ncbi.nlm.nih.gov/pubmed/21363960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.2021311
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