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Monocyte Chemoattractant Protein–1 Blockade Inhibits Lung Cancer Tumor Growth by Altering Macrophage Phenotype and Activating CD8(+) Cells

The role of chemokines in the pathogenesis of lung cancer has been increasingly appreciated. Monocyte chemoattractant protein–1 (MCP-1, also known as CCL2) is secreted from tumor cells and associated tumor stromal cells. The blockade of CCL2, as mediated by neutralizing antibodies, was shown to redu...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Fridlender, Zvi G., Kapoor, Veena, Buchlis, George, Cheng, Guanjun, Sun, Jing, Wang, Liang-Chuan S., Singhal, Sunil, Snyder, Linda A., Albelda, Steven M.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Thoracic Society 2011
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3049234/
https://ncbi.nlm.nih.gov/pubmed/20395632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2010-0080OC
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