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A New Function for LAT and CD8 During CD8-Mediated Apoptosis that is Independent of T Cell Receptor Signal Transduction

The majority (>95%) of thymocytes undergo apoptosis during selection in the thymus. Several mechanisms have been proposed to explain how apoptosis of thymocytes that are not positively selected occurs, however it is unknown whether thymocytes die purely by “neglect” or whether signaling through a...

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Detalhes bibliográficos
Main Authors: Clarke, Raedun L, Thiemann, Sandra, Refaeli, Yosef, Werlen, Guy, Potter, Terry A
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3049189/
https://ncbi.nlm.nih.gov/pubmed/19449311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200839062
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