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An Isothermal System that Couples Ligand-dependent Catalysis to Ligand-independent Exponential Amplification
A system was devised that enables quantitative, ligand-dependent exponential amplification for various ligands that can be recognized by an RNA aptamer. The aptamer is linked to an RNA enzyme that catalyzes the joining of two oligonucleotide substrates. The product of this reaction is another RNA en...
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| Huvudupphovsmän: | , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2011
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3048896/ https://ncbi.nlm.nih.gov/pubmed/21322594 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja111136d |
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