Inhibitory Effect of TNF-α on Malaria Pre-Erythrocytic Stage Development: Influence of Host Hepatocyte/Parasite Combinations

BACKGROUND: The liver stages of malaria parasites are inhibited by cytokines such as interferon-γ or Interleukin (IL)-6. Binding of these cytokines to their receptors at the surface of the infected hepatocytes leads to the production of nitric oxide (NO) and radical oxygen intermediates (ROI), which...

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Autori principali: Depinay, Nadya, Franetich, Jean Francois, Grüner, Anne Charlotte, Mauduit, Marjorie, Chavatte, Jean-Marc, Luty, Adrian J. F., van Gemert, Geert-Jan, Sauerwein, Robert W., Siksik, Jean-Michel, Hannoun, Laurent, Mazier, Dominique, Snounou, Georges, Rénia, Laurent
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048870/
https://ncbi.nlm.nih.gov/pubmed/21394207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017464
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