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IL-1β Stimulates COX-2 Dependent PGE(2) Synthesis and CGRP Release in Rat Trigeminal Ganglia Cells
OBJECTIVE: Pro-inflammatory cytokines like Interleukin-1 beta (IL-1β) have been implicated in the pathophysiology of migraine and inflammatory pain. The trigeminal ganglion and calcitonin gene-related peptide (CGRP) are crucial components in the pathophysiology of primary headaches. 5-HT1B/D recepto...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3048859/ https://ncbi.nlm.nih.gov/pubmed/21394197 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017360 |
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