Two TRPV1 receptor antagonists are effective in two different experimental models of migraine

BACKGROUND: The capsaicin and heat responsive ion channel TRPV1 is expressed on trigeminal nociceptive neurons and has been implicated in the pathophysiology of migraine attacks. Here we investigate the efficacy of two TRPV1 channel antagonists in blocking trigeminal activation using two in vivo mod...

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Detaylı Bibliyografya
Yayımlandı:J Headache Pain
Asıl Yazarlar: Meents, Jannis E, Hoffmann, Jan, Chaplan, Sandra R, Neeb, Lars, Schuh-Hofer, Sigrid, Wickenden, Alan, Reuter, Uwe
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Springer Milan 2015
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4491068/
https://ncbi.nlm.nih.gov/pubmed/26109436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s10194-015-0539-z
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