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Two TRPV1 receptor antagonists are effective in two different experimental models of migraine

BACKGROUND: The capsaicin and heat responsive ion channel TRPV1 is expressed on trigeminal nociceptive neurons and has been implicated in the pathophysiology of migraine attacks. Here we investigate the efficacy of two TRPV1 channel antagonists in blocking trigeminal activation using two in vivo mod...

詳細記述

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書誌詳細
出版年:J Headache Pain
主要な著者: Meents, Jannis E, Hoffmann, Jan, Chaplan, Sandra R, Neeb, Lars, Schuh-Hofer, Sigrid, Wickenden, Alan, Reuter, Uwe
フォーマット: Artigo
言語:Inglês
出版事項: Springer Milan 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4491068/
https://ncbi.nlm.nih.gov/pubmed/26109436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s10194-015-0539-z
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