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Two TRPV1 receptor antagonists are effective in two different experimental models of migraine

BACKGROUND: The capsaicin and heat responsive ion channel TRPV1 is expressed on trigeminal nociceptive neurons and has been implicated in the pathophysiology of migraine attacks. Here we investigate the efficacy of two TRPV1 channel antagonists in blocking trigeminal activation using two in vivo mod...

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Bibliografski detalji
Izdano u:J Headache Pain
Glavni autori: Meents, Jannis E, Hoffmann, Jan, Chaplan, Sandra R, Neeb, Lars, Schuh-Hofer, Sigrid, Wickenden, Alan, Reuter, Uwe
Format: Artigo
Jezik:Inglês
Izdano: Springer Milan 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4491068/
https://ncbi.nlm.nih.gov/pubmed/26109436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s10194-015-0539-z
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