Recognition of Alzheimer paired helical filaments by monoclonal neurofilament antibodies is due to crossreaction with tau protein.
Neurofibrillary tangles and senile plaques are the principal pathological features of Alzheimer disease. Neurofibrillary tangles and the neurites of senile plaques contain paired helical filaments (PHF) that consist of two 10-nm filaments twisted into a double helix. The precursor proteins of PHF ar...
में बचाया:
| में प्रकाशित: | Proc Natl Acad Sci U S A |
|---|---|
| मुख्य लेखकों: | , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
National Academy of Sciences
1987
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304881/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3106969/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.10.3415 |
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