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Protein Kinase C-dependent Ubiquitination and Clathrin-mediated Endocytosis of the Cationic Amino Acid Transporter CAT-1

Cationic amino acid transporter 1 (CAT-1) is responsible for the bulk of the uptake of cationic amino acids in most mammalian cells. Activation of protein kinase C (PKC) leads to down-regulation of the cell surface CAT-1. To examine the mechanisms of PKC-induced down-regulation of CAT-1, a functiona...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Vina-Vilaseca, Arnau, Bender-Sigel, Julia, Sorkina, Tatiana, Closs, Ellen Ildicho, Sorkin, Alexander
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048751/
https://ncbi.nlm.nih.gov/pubmed/21212261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.186858
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