POSH Stimulates the Ubiquitination and the Clathrin-independent Endocytosis of ROMK1 Channels

POSH (plenty of SH3) is a scaffold protein that has been shown to act as an E3 ubiquitin ligase. Here we report that POSH stimulates the ubiquitination of Kir1.1 (ROMK) and enhances the internalization of this potassium channel. Immunostaining reveals the expression of POSH in the renal cortical col...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Lin, Dao-Hong, Yue, Peng, Pan, Chu-Yang, Sun, Peng, Zhang, Xin, Han, Zeguang, Roos, Marcel, Caplan, Michael, Giebisch, Gerhard, Wang, Wen-Hui
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2009
Pynciau:
Membrane Transport, Structure, Function, and Biogenesis
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785594/
https://ncbi.nlm.nih.gov/pubmed/19710010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.041582
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