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Tethering Function of the Caspase Cleavage Fragment of Golgi Protein p115 Promotes Apoptosis via a p53-dependent Pathway

The Golgi apparatus undergoes extensive fragmentation during apoptosis due in part to caspase-mediated cleavage of its structural proteins. Significantly, the Golgi-vesicle-tethering protein p115 is cleaved at Asp(757) early during apoptosis and the nuclear translocation of its 205 amino acid C-term...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: How, Poh Choo, Shields, Dennis
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048739/
https://ncbi.nlm.nih.gov/pubmed/21147777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.175174
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