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A caspase cleavage fragment of p115 induces fragmentation of the Golgi apparatus and apoptosis

In mammalian cells, the Golgi apparatus undergoes extensive fragmentation during apoptosis. p115 is a key vesicle tethering protein required for maintaining the structural organization of the Golgi apparatus. Here, we demonstrate that p115 was cleaved during apoptosis by caspases 3 and 8. Compared w...

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Библиографические подробности
Главные авторы: Chiu, Raymond, Novikov, Leonid, Mukherjee, Shaeri, Shields, Dennis
Формат: Artigo
Язык:Inglês
Опубликовано: The Rockefeller University Press 2002
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173109/
https://ncbi.nlm.nih.gov/pubmed/12438416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200208013
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