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A caspase cleavage fragment of p115 induces fragmentation of the Golgi apparatus and apoptosis
In mammalian cells, the Golgi apparatus undergoes extensive fragmentation during apoptosis. p115 is a key vesicle tethering protein required for maintaining the structural organization of the Golgi apparatus. Here, we demonstrate that p115 was cleaved during apoptosis by caspases 3 and 8. Compared w...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Rockefeller University Press
2002
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2173109/ https://ncbi.nlm.nih.gov/pubmed/12438416 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200208013 |
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