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Nuclear Import Is Required for the Pro-apoptotic Function of the Golgi Protein p115

During apoptosis the Golgi apparatus undergoes irreversible fragmentation. In part, this results from caspase-mediated cleavage of several high molecular weight coiled-coil proteins, termed golgins. These include GM130, golgin 160, and the Golgi vesicle tethering protein p115, whose caspase cleavage...

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Bibliografiske detaljer
Main Authors: Mukherjee, Shaeri, Shields, Dennis
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2615508/
https://ncbi.nlm.nih.gov/pubmed/19028683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807263200
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