Fungal Recognition Enhances Mannose Receptor Shedding through Dectin-1 Engagement

The mannose receptor (MR) is an endocytic type I membrane molecule with a broad ligand specificity that is involved in both hemostasis and pathogen recognition. Membrane-anchored MR is cleaved by a metalloproteinase into functional soluble MR (sMR) composed of the extracellular domains of intact MR....

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Main Authors: Gazi, Umut, Rosas, Marcela, Singh, Sonali, Heinsbroek, Sigrid, Haq, Imran, Johnson, Simon, Brown, Gordon D., Williams, David L., Taylor, Philip R., Martinez-Pomares, Luisa
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2011
Teme:
Immunology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048669/
https://ncbi.nlm.nih.gov/pubmed/21205820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.185025
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