Lanean...

Viral Double-stranded RNAs from Vaccinia Virus Early or Intermediate Gene Transcripts Possess PKR Activating Function, Resulting in NF-κB Activation, When the K1 Protein Is Absent or Mutated

PKR is a potent antiviral molecule that can terminate infection by inhibiting protein synthesis and stimulating NF-κB activation and apoptosis. Originally, it was thought that only intermediate and late gene transcription produced double-stranded (ds) RNA to activate PKR during vaccinia virus (VACV)...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Willis, Kristen L., Langland, Jeffrey O., Shisler, Joanna L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048664/
https://ncbi.nlm.nih.gov/pubmed/21183678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.194704
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!