HSV Delivery of a Ligand-regulated Endogenous Ion Channel Gene to Sensory Neurons Results in Pain Control Following Channel Activation

Persistent pain remains a tremendous health problem due to both its prevalence and dearth of effective therapeutic interventions. To maximize pain relief while minimizing side effects, current gene therapy–based approaches have mostly exploited the expression of pain inhibitory products or interfere...

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Detalhes bibliográficos
Main Authors: Goss, James R, Cascio, Michael, Goins, William F, Huang, Shaohua, Krisky, David M, Clarke, Richard J, Johnson, Jon W, Yokoyama, Hitoshi, Yoshimura, Naoki, Gold, Michael S, Glorioso, Joseph C
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048176/
https://ncbi.nlm.nih.gov/pubmed/21081904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.246
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