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Activation of the NF-κB pathway by adeno-associated virus (AAV) vectors and its implications in immune response and gene therapy

Because our in silico analysis with a human transcription factor database demonstrated the presence of several binding sites for NF-κB, a central regulator of cellular immune and inflammatory responses, in the adeno-associated virus (AAV) genome, we investigated whether AAV uses NF-κB during its lif...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Jayandharan, Giridhara R., Aslanidi, George, Martino, Ashley T., Jahn, Stephan C., Perrin, George Q., Herzog, Roland W., Srivastava, Arun
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048154/
https://ncbi.nlm.nih.gov/pubmed/21321191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1012753108
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