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Merlin's tumor suppression linked to inhibition of the E3 ubiquitin ligase CRL4(DCAF1)

The mechanism by which the FERM domain protein Merlin, encoded by the tumor suppressor NF2, restrains cell proliferation is poorly understood. Prior studies have suggested that Merlin exerts its antimitogenic effect by interacting with multiple signaling proteins located at or near the plasma membra...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Li, Wei, Giancotti, Filippo G
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Landes Bioscience 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048042/
https://ncbi.nlm.nih.gov/pubmed/21084862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.9.22.13838
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