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Ku80 facilitates chromatin binding of the telomere binding protein, TRF2

The Ku70/80 heterodimer is central to non-homologous end joining repair of DNA double-strand breaks and the Ku80 gene appears to be essential for human but not rodent cell survival. The Ku70/80 heterodimer is located at telomeres but its precise function in telomere maintenance is not known. In orde...

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Detalhes bibliográficos
Main Authors: Fink, Lauren S, Lerner, Chad A, Torres, Paulina F, Sell, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3047804/
https://ncbi.nlm.nih.gov/pubmed/20890109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.9.18.13129
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