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Ku80 facilitates chromatin binding of the telomere binding protein, TRF2

The Ku70/80 heterodimer is central to non-homologous end joining repair of DNA double-strand breaks and the Ku80 gene appears to be essential for human but not rodent cell survival. The Ku70/80 heterodimer is located at telomeres but its precise function in telomere maintenance is not known. In orde...

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Hlavní autoři: Fink, Lauren S, Lerner, Chad A, Torres, Paulina F, Sell, Christian
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3047804/
https://ncbi.nlm.nih.gov/pubmed/20890109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.9.18.13129
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