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Evolutionary dynamics of two related malignant plasma cell lines

Cancer is the consequence of sequential acquisition of mutations within somatic cells. Mutations alter the relative reproductive fitness of cells, enabling the population to evolve in time as a consequence of selection. Cancer therapy itself can select for or against specific subclones. Given the la...

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Autors principals: Dingli, David, Arendt, Bonnie K, Bajzer, Željko, Jelinek, Diane F
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3047803/
https://ncbi.nlm.nih.gov/pubmed/20890105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.9.18.13047
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