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Evolutionary dynamics of two related malignant plasma cell lines
Cancer is the consequence of sequential acquisition of mutations within somatic cells. Mutations alter the relative reproductive fitness of cells, enabling the population to evolve in time as a consequence of selection. Cancer therapy itself can select for or against specific subclones. Given the la...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Landes Bioscience
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3047803/ https://ncbi.nlm.nih.gov/pubmed/20890105 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.9.18.13047 |
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