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N-terminal transmembrane domain of SUR1 controls gating of Kir6.2 by modulating channel sensitivity to PIP(2)

Functional integrity of pancreatic adenosine triphosphate (ATP)-sensitive potassium (K(ATP)) channels depends on the interactions between the pore-forming potassium channel subunit Kir6.2 and the regulatory subunit sulfonylurea receptor 1 (SUR1). Previous studies have shown that the N-terminal trans...

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Hlavní autoři: Pratt, Emily B., Tewson, Paul, Bruederle, Cathrin E., Skach, William R., Shyng, Show-Ling
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3047609/
https://ncbi.nlm.nih.gov/pubmed/21321069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201010557
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