Uracil DNA N-Glycosylase Promotes Assembly of Human Centromere Protein A

Uracil is removed from DNA by the conserved enzyme Uracil DNA N-glycosylase (UNG). Previously, we observed that inhibiting UNG in Xenopus egg extracts blocked assembly of CENP-A, a histone H3 variant. CENP-A is an essential protein in all species, since it is required for chromosome segregation duri...

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Detaylı Bibliyografya
Asıl Yazarlar: Zeitlin, Samantha G., Chapados, Brian R., Baker, Norman M., Tai, Caroline, Slupphaug, Geir, Wang, Jean Y. J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2011
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3047565/
https://ncbi.nlm.nih.gov/pubmed/21399697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017151
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