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Uracil DNA N-Glycosylase Promotes Assembly of Human Centromere Protein A
Uracil is removed from DNA by the conserved enzyme Uracil DNA N-glycosylase (UNG). Previously, we observed that inhibiting UNG in Xenopus egg extracts blocked assembly of CENP-A, a histone H3 variant. CENP-A is an essential protein in all species, since it is required for chromosome segregation duri...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3047565/ https://ncbi.nlm.nih.gov/pubmed/21399697 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017151 |
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