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TRPM2, calcium and neurodegenerative diseases

NMDA receptor overactivation triggers intracellular Ca(2+) dysregulation, which has long been thought to be critical for initiating excitotoxic cell death cascades associated with stroke and neurodegenerative disease. The inability of NMDA receptor antagonists to afford neuroprotection in clinical s...

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Bibliografische gegevens
Hoofdauteurs: Xie, Yu-Feng, MacDonald, John F, Jackson, Michael F
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: e-Century Publishing Corporation 2010
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3047260/
https://ncbi.nlm.nih.gov/pubmed/21383889
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