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TRPM2, calcium and neurodegenerative diseases

NMDA receptor overactivation triggers intracellular Ca(2+) dysregulation, which has long been thought to be critical for initiating excitotoxic cell death cascades associated with stroke and neurodegenerative disease. The inability of NMDA receptor antagonists to afford neuroprotection in clinical s...

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Detalhes bibliográficos
Main Authors: Xie, Yu-Feng, MacDonald, John F, Jackson, Michael F
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3047260/
https://ncbi.nlm.nih.gov/pubmed/21383889
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