p53 governs telomere regulation feedback too, via TRF2

p53 takes critical part in a number of positive and negative feedback loops to regulate carcinogenesis, aging and other biological processes. Uncapped or dysfunctional telomeres are an endogenous DNA damage that activates ATM kinase (ataxia telangiectasia mutated) and then p53 to induce cellular sen...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Horikawa, Izumi, Fujita, Kaori, Harris, Curtis C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Impact Journals LLC 2011
Gaiak:
Research Perspective
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3047136/
https://ncbi.nlm.nih.gov/pubmed/21266744
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak