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Immune modulation with weekly dosing of an agonist CD40 antibody in a phase I study of patients with advanced solid tumors
BACKGROUND: Single-dose infusion of the agonistic anti-CD40 monoclonal antibody (mAb) CP-870,893 accomplishes immune activation and clinical responses in patients with advanced cancers, but repeat dosing of this agent has not been reported. RESULTS: Twenty-seven patients were enrolled. The most comm...
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| Hoofdauteurs: | , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Landes Bioscience
2010
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3047092/ https://ncbi.nlm.nih.gov/pubmed/20855968 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.10.10.13251 |
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