PIK3CA mutations and EGFR overexpression predict for lithium sensitivity in human breast epithelial cells

A high frequency of somatic mutations has been found in breast cancers within the gene encoding the catalytic p110α subunit of PI3K, PIK3CA. Using isogenic human breast epithelial cells, we have previously demonstrated that oncogenic PIK3CA “hotspot” mutations predict for response to the toxic effec...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Higgins, Michaela J, Beaver, Julia A, Wong, Hong yuen, Gustin, John P, Lauring, Josh D, Garay, Joseph P, Konishi, Hiroyuki, Mohseni, Morassa, Wang, Grace M, Cidado, Justin, Jelovac, Danijela, Cosgrove, David P, Tamaki, Akina, Abukhdeir, Abde M, Park, Ben Ho
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2011
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3047087/
https://ncbi.nlm.nih.gov/pubmed/21124076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.11.3.14227
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados