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The Nrf2 transcription factor is a positive regulator of myeloid differentiation of acute myeloid leukemia cells

1α,25-dihydroxyvitamin D(3) (1,25D) is a powerful differentiation agent, which has potential for treatment of acute myeloid leukemia (AML), but induces severe hypercalcemia at pharmacologically active doses. We have previously shown that carnosic acid (CA), the polyphenolic antioxidant from rosemary...

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Detalhes bibliográficos
Main Authors: Bobilev, Irene, Novik, Victoria, Levi, Itai, Shpilberg, Ofer, Levy, Joseph, Sharoni, Yoav, Studzinski, George P, Danilenko, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3047086/
https://ncbi.nlm.nih.gov/pubmed/21099366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.11.3.14098
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