Synergistic Antileukemic Activity of Carnosic Acid-Rich Rosemary Extract and the 19-nor Gemini Vitamin D Analogue in a Mouse Model of Systemic Acute Myeloid Leukemia

OBJECTIVE: Differentiation therapy with the hormonal form of vitamin D, 1α,25-dihydroxyvitamin D(3) (1,25D(3)), is a promising approach to treatment of acute myeloid leukemia (AML); however, 1,25D(3) induces hypercalcemia at pharmacologically active doses. We investigated the in vitro and in vivoant...

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Bibliographische Detailangaben
Hauptverfasser: Shabtay, Ayelet, Sharabani, Hagar, Barvish, Zeev, Kafka, Michael, Amichay, Doron, Levy, Joseph, Sharoni, Yoav, Uskokovic, Milan R., Studzinski, George P., Danilenko, Michael
Format: Artigo
Sprache:Inglês
Veröffentlicht: S. Karger AG 2008
Schlagworte:
Clinical Translational Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2826875/
https://ncbi.nlm.nih.gov/pubmed/18852491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000163849
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