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Distinct combinatorial effects of the plant polyphenols curcumin, carnosic acid and silibinin on proliferation and apoptosis in acute myeloid leukemia cells

Acute myeloid leukemia (AML) is a malignancy without effective treatment for most patients. Here we demonstrate that combinations of the dietary plant polyphenols curcumin and carnosic acid, at non-cytotoxic concentrations of each agent, produced a synergistic antiproliferative effect and a massive...

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Detalhes bibliográficos
Main Authors: Pesakhov, Stella, Khanin, Marina, Studzinski, George P., Danilenko, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2911976/
https://ncbi.nlm.nih.gov/pubmed/20661831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/01635581003693082
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