The Nrf2 transcription factor is a positive regulator of myeloid differentiation of acute myeloid leukemia cells

1α,25-dihydroxyvitamin D(3) (1,25D) is a powerful differentiation agent, which has potential for treatment of acute myeloid leukemia (AML), but induces severe hypercalcemia at pharmacologically active doses. We have previously shown that carnosic acid (CA), the polyphenolic antioxidant from rosemary...

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Autori principali: Bobilev, Irene, Novik, Victoria, Levi, Itai, Shpilberg, Ofer, Levy, Joseph, Sharoni, Yoav, Studzinski, George P, Danilenko, Michael
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2011
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3047086/
https://ncbi.nlm.nih.gov/pubmed/21099366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.11.3.14098
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