Ongoing β-Cell Turnover in Adult Nonhuman Primates Is Not Adaptively Increased in Streptozotocin-Induced Diabetes

OBJECTIVE: β-Cell turnover and its potential to permit β-cell regeneration in adult primates are unknown. Our aims were 1) to measure β-cell turnover in adult nonhuman primates; 2) to establish the relative contribution of β-cell replication and formation of new β-cells from other precursors (define...

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Autors principals: Saisho, Yoshifumi, Manesso, Erica, Butler, Alexandra E., Galasso, Ryan, Kavanagh, Kylie, Flynn, Mickey, Zhang, Li, Clark, Paige, Gurlo, Tatyana, Toffolo, Gianna M., Cobelli, Claudio, Wagner, Janice D., Butler, Peter C.
Format: Artigo
Idioma:Inglês
Publicat: American Diabetes Association 2011
Matèries:
Islet Studies
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3046845/
https://ncbi.nlm.nih.gov/pubmed/21270238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db09-1368
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