Molecular Mechanism by Which AMP-Activated Protein Kinase Activation Promotes Glycogen Accumulation in Muscle

OBJECTIVE: During energy stress, AMP-activated protein kinase (AMPK) promotes glucose transport and glycolysis for ATP production, while it is thought to inhibit anabolic glycogen synthesis by suppressing the activity of glycogen synthase (GS) to maintain the energy balance in muscle. Paradoxically,...

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Autores principales: Hunter, Roger W., Treebak, Jonas T., Wojtaszewski, Jørgen F.P., Sakamoto, Kei
Formato: Artigo
Lenguaje:Inglês
Publicado: American Diabetes Association 2011
Materias:
Metabolism
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3046837/
https://ncbi.nlm.nih.gov/pubmed/21282366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db10-1148
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