AMP-activated protein kinase regulates nicotinamide phosphoribosyl transferase expression in skeletal muscle

Deacetylases such as sirtuins (SIRTs) convert NAD to nicotinamide (NAM). Nicotinamide phosphoribosyl transferase (Nampt) is the rate-limiting enzyme in the NAD salvage pathway responsible for converting NAM to NAD to maintain cellular redox state. Activation of AMP-activated protein kinase (AMPK) in...

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Bibliographische Detailangaben
Hauptverfasser: Brandauer, Josef, Vienberg, Sara G, Andersen, Marianne A, Ringholm, Stine, Risis, Steve, Larsen, Per S, Kristensen, Jonas M, Frøsig, Christian, Leick, Lotte, Fentz, Joachim, Jørgensen, Sebastian, Kiens, Bente, Wojtaszewski, Jørgen F P, Richter, Erik A, Zierath, Juleen R, Goodyear, Laurie J, Pilegaard, Henriette, Treebak, Jonas T
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Science Inc 2013
Schlagworte:
Skeletal Muscle and Exercise
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3810819/
https://ncbi.nlm.nih.gov/pubmed/23918774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2013.259515
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