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Two weeks of metformin treatment induces AMPK-dependent enhancement of insulin-stimulated glucose uptake in mouse soleus muscle

Metformin-induced activation of the 5′-AMP-activated protein kinase (AMPK) has been associated with enhanced glucose uptake in skeletal muscle, but so far no direct causality has been examined. We hypothesized that an effect of in vivo metformin treatment on glucose uptake in mouse skeletal muscles...

詳細記述

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書誌詳細
出版年:Am J Physiol Endocrinol Metab
主要な著者: Kristensen, Jonas Møller, Treebak, Jonas T., Schjerling, Peter, Goodyear, Laurie, Wojtaszewski, Jørgen F. P.
フォーマット: Artigo
言語:Inglês
出版事項: American Physiological Society 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4971810/
https://ncbi.nlm.nih.gov/pubmed/24644243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00417.2013
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