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Two Weeks of Metformin Treatment Enhances Mitochondrial Respiration in Skeletal Muscle of AMPK Kinase Dead but Not Wild Type Mice

Metformin is used as an anti-diabetic drug. Metformin ameliorates insulin resistance by improving insulin sensitivity in liver and skeletal muscle. Reduced mitochondrial content has been reported in type 2 diabetic muscles and it may contribute to decreased insulin sensitivity characteristic for dia...

詳細記述

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書誌詳細
主要な著者: Kristensen, Jonas M., Larsen, Steen, Helge, Jørn W., Dela, Flemming, Wojtaszewski, Jørgen F. P.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3544921/
https://ncbi.nlm.nih.gov/pubmed/23341947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053533
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