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Mendelian Randomization Studies Do Not Support a Role for Raised Circulating Triglyceride Levels Influencing Type 2 Diabetes, Glucose Levels, or Insulin Resistance

OBJECTIVE: The causal nature of associations between circulating triglycerides, insulin resistance, and type 2 diabetes is unclear. We aimed to use Mendelian randomization to test the hypothesis that raised circulating triglyceride levels causally influence the risk of type 2 diabetes and raise norm...

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Bibliografski detalji
Glavni autori: De Silva, N. Maneka G., Freathy, Rachel M., Palmer, Tom M., Donnelly, Louise A., Luan, Jian'an, Gaunt, Tom, Langenberg, Claudia, Weedon, Michael N., Shields, Beverley, Knight, Beatrice A., Ward, Kirsten J., Sandhu, Manjinder S., Harbord, Roger M., McCarthy, Mark I., Smith, George Davey, Ebrahim, Shah, Hattersley, Andrew T., Wareham, Nicholas, Lawlor, Debbie A., Morris, Andrew D., Palmer, Colin N.A., Frayling, Timothy M.
Format: Artigo
Jezik:Inglês
Izdano: American Diabetes Association 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3046819/
https://ncbi.nlm.nih.gov/pubmed/21282362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db10-1317
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