Loading of oncolytic vesicular stomatitis virus onto antigen-specific T cells enhances the efficacy of adoptive T-cell therapy of tumors

Although adoptive T-cell therapy has shown clinical success, efficacy is limited by low levels of T-cell trafficking to, and survival in, the immunosuppressive environment of an established tumor. Oncolytic virotherapy has recently emerged as a promising approach to induce both direct tumor cell kil...

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Detalhes bibliográficos
Main Authors: Qiao, J, Wang, H, Kottke, T, Diaz, RM, Willmon, C, Hudacek, A, Thompson, J, Parato, K, Bell, J, Naik, J, Chester, J, Selby, P, Harrington, K, Melcher, A, Vile, RG
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3046771/
https://ncbi.nlm.nih.gov/pubmed/18305577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.gt.3303098
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