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Epigenetic changes play critical role in age-associated dysfunctions of the liver

C/EBP family proteins are important regulators of liver functions. Here we show the critical role of C/EBPα-mediated chromatin remodeling in the age-associated dysfunctions of the liver and in the maintenance of physiological homeostasis. Because ph-S193 isoform of C/EBPα is increased in livers of o...

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Detalhes bibliográficos
Main Authors: Jin, Jingling, Wang, Guo-Li, Iakova, Polina, Shi, Xiurong, Haefliger, Simon, Finegold, Milton, Timchenko, Nikolai A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3046424/
https://ncbi.nlm.nih.gov/pubmed/20698834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1474-9726.2010.00617.x
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